RT Journal Article T1 Multidisciplinary Tinnitus Research: Challenges and Future Directions From the Perspective of Early Stage Researchers. A1 Simoes, Jorge Piano A1 Daoud, Elza A1 Shabbir, Maryam A1 Amanat, Sana A1 Assouly, Kelly A1 Biswas, Roshni A1 Casolani, Chiara A1 Dode, Albi A1 Enzler, Falco A1 Jacquemin, Laure A1 Joergensen, Mie A1 Kok, Tori A1 Liyanage, Nuwan A1 Lourenco, Matheus A1 Makani, Punitkumar A1 Mehdi, Muntazir A1 Ramadhani, Anissa L A1 Riha, Constanze A1 Santacruz, Jose Lopez A1 Schiller, Axel A1 Schoisswohl, Stefan A1 Trpchevska, Natalia A1 Genitsaridi, Eleni K1 big data K1 heterogeneity K1 interdisciplinary collaborations K1 review K1 standardization K1 tinnitus K1 treatment development AB Tinnitus can be a burdensome condition on both individual and societal levels. Many aspects of this condition remain elusive, including its underlying mechanisms, ultimately hindering the development of a cure. Interdisciplinary approaches are required to overcome long-established research challenges. This review summarizes current knowledge in various tinnitus-relevant research fields including tinnitus generating mechanisms, heterogeneity, epidemiology, assessment, and treatment development, in an effort to highlight the main challenges and provide suggestions for future research to overcome them. Four common themes across different areas were identified as future research direction: (1) Further establishment of multicenter and multidisciplinary collaborations; (2) Systematic reviews and syntheses of existing knowledge; (3) Standardization of research methods including tinnitus assessment, data acquisition, and data analysis protocols; (4) The design of studies with large sample sizes and the creation of large tinnitus-specific databases that would allow in-depth exploration of tinnitus heterogeneity. SN 1663-4365 YR 2021 FD 2021-06-11 LK http://hdl.handle.net/10668/18048 UL http://hdl.handle.net/10668/18048 LA en DS RISalud RD Apr 17, 2025