RT Journal Article
T1 Cumulative dietary risk assessment of chronic acetylcholinesterase inhibition by residues of pesticides.
A1 European Food Safety Authority (EFSA), 
A1 Anastassiadou, Maria
A1 Choi, Judy
A1 Coja, Tamara
A1 Dujardin, Bruno
A1 Hart, Andy
A1 Hernandez-Jerrez, Antonio F
A1 Jarrah, Samira
A1 Lostia, Alfonso
A1 Machera, Kyriaki
A1 Mangas, Iris
A1 Mienne, Alexandra
A1 Schepens, Marloes
A1 Widenfalk, Anneli
A1 Mohimont, Luc
K1 acetylcholinesterase inhibition
K1 cumulative risk assessment
K1 knowledge elicitation
K1 pesticide residues
K1 probabilistic modelling
AB A retrospective cumulative risk assessment of dietary exposure to pesticide residues was conducted for chronic inhibition of acetylcholinesterase. The pesticides considered in this assessment were identified and characterised in a previous scientific report on the establishment of cumulative assessment groups of pesticides for their effects on the nervous system. The exposure assessments used monitoring data collected by Member States under their official pesticide monitoring programmes in 2016, 2017 and 2018, and individual food consumption data from 10 populations of consumers from different countries and from different age groups. Exposure estimates were obtained by means of a two-dimensional probabilistic model, which was implemented in SAS ® software. The characterisation of cumulative risk was supported by an uncertainty analysis based on expert knowledge elicitation. For each of the 10 populations, it is concluded with varying degrees of certainty that cumulative exposure to pesticides contributing to the chronic inhibition of acetylcholinesterase does not exceed the threshold for regulatory consideration established by risk managers.
YR 2021
FD 2021-02-10
LK https://hdl.handle.net/10668/26737
UL https://hdl.handle.net/10668/26737
LA en
DS RISalud
RD Apr 8, 2025