RT Journal Article T1 [Triple synchronous primary gynaecological tumours. A case report]. T2 Tumores triple sincrónicos ginecológicos. Reporte de un caso. A1 Gutiérrez-Palomino, Laura A1 Romo-de Los Reyes, José María A1 Pareja-Megía, María Jesús A1 García-Mejido, José Antonio K1 Cáncer de endometrio K1 Cáncer de ovario K1 Cáncer tubular K1 Endometrial cancer K1 Fallopian tube cancer K1 Multiple synchronous cancers K1 Neoplasias sincrónicas K1 Neoplasias sincrónicas múltiples K1 Ovarian cancer K1 Synchronous cancers AB Synchronous multiple primary malignancies in the female genital tract are infrequent. From 50 to 70% of them corresponds to synchronous cancers of the endometrium and ovary. To our knowledge, this is only the third case report in the international literature of three concurrent gynaecological cancers of epithelial origin. A case is presented, as well as a literature review due to the infrequency of its diagnosis and the lack of information on the subject. A 49-year-old woman, with previous gynaecological history of ovarian endometriosis. She underwent a hysterectomy and bilateral oophorectomy, as she had been diagnosed with endometrial hyperplasia with atypia. The final histopathology reported synchronous ovarian, Fallopian tube, and endometrial cancer. An extension study and complete surgical staging was performed, both being negative. She received adjuvant treatment of chemotherapy and radiotherapy. She is currently free of disease. The aetiology is uncertain. There is controversy relating to increased susceptibility of synchronous neoplasms to pelvic endometriosis and inherited genetic syndromes. Its diagnosis needs to differentiate them from metastatic disease. Additionally, they are problematical from a clinical, diagnostic, therapeutic, and prognostic point of view. The presentation of more cases of triple synchronous cancers is necessary for a complete adjuvant and surgical treatment. YR 2015 FD 2015-08-01 LK http://hdl.handle.net/10668/10072 UL http://hdl.handle.net/10668/10072 LA es DS RISalud RD Apr 19, 2025