RT Journal Article T1 Impact of physical exercise in patients with chronic kidney disease: Sistematic review and meta-analysis. T2 Impacto del ejercicio físico en pacientes con enfermedad renal crónica: revisión sistemática y metaanálisis. A1 Villanego, Florentino A1 Naranjo, Javier A1 Vigara, Luis Alberto A1 Cazorla, Juan Manuel A1 Montero, Maria Elisa A1 García, Teresa A1 Torrado, Julia A1 Mazuecos, Auxiliadora K1 Chronic kidney disease K1 Dialysis K1 Diálisis K1 Ejercicio físico K1 Enfermedad renal crónica K1 Meta-analysis K1 Metaanálisis K1 Physical activity K1 Revision K1 Revisión AB Physical exercise may offer multiple benefits to patients with chronic kidney disease (CKD). However, it was not traditionally recommended because of the possibility of impairing renal function and increasing proteinuria. The objective of this study is to review the clinical trials on physical exercise in patients with CKD and describe its effect on the progression of kidney disease and other factors associated. Randomized clinical trials (RCT) comparing an intervention that included an exercise component with a control group without physical exercise in non-dialysis patients with CKD from 2007 to 2018 in English and Spanish were included. PubMed, Scopus, Embase, Ovid (Medline) and PEDro databases were used for the search. Effects of physical exercise were summarized by the standardized mean difference (SMD). No differences were found in glomerular filtration rate or proteinuria between the intervention group and the control group: SMD -0.3 (P=.81); SMD 26.6 (P=.82). Positive effects were obtained on peak oxygen consumption: SMD 2.5 (P YR 2020 FD 2020-04-15 LK http://hdl.handle.net/10668/15392 UL http://hdl.handle.net/10668/15392 LA en LA es DS RISalud RD Apr 18, 2025