TY - JOUR AU - López-Gómez, Carlos AU - Pino-Ángeles, Almudena AU - Órpez-Zafra, Teresa AU - Pinto-Medel, María Jesús AU - Oliver-Martos, Begoña AU - Ortega-Pinazo, Jesús AU - Arnáiz, Carlos AU - Guijarro-Castro, Cristina AU - Varadé, Jezabel AU - Álvarez-Lafuente, Roberto AU - Urcelay, Elena AU - Sánchez-Jiménez, Francisca AU - Fernández, Óscar AU - Leyva, Laura PY - 2013 DO - 10.1371/journal.pone.0062540 UR - http://hdl.handle.net/10668/1330 T2 - PloS one AB - TRAIL and TRAIL Receptor genes have been implicated in Multiple Sclerosis pathology as well as in the response to IFN beta therapy. The objective of our study was to evaluate the association of these genes in relation to the age at disease onset (AAO)... LA - en PB - Public Library of Science KW - Esclerosis múltiple KW - España KW - Genotipo KW - Ácido glutámico KW - Alanina KW - Edad de Inicio KW - Medical Subject Headings::Diseases::Nervous System Diseases::Autoimmune Diseases of the Nervous System::Demyelinating Autoimmune Diseases, CNS::Multiple Sclerosis KW - Medical Subject Headings::Geographicals::Geographic Locations::Europe::Spain KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genotype KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Amino Acids::Amino Acids, Acidic KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Amino Acids::Alanine KW - Medical Subject Headings::Health Care::Environment and Public Health::Public Health::Epidemiologic Factors::Age Factors::Age of Onset TI - Candidate gene study of TRAIL and TRAIL receptors: association with response to interferon beta therapy in multiple sclerosis patients. TY - research article ER -