RT Journal Article
T1 Early outcomes of kidney transplantation from elderly donors after circulatory death (GEODAS study).
A1 Perez-Saez, Maria Jose
A1 Lafuente-Covarrubias, Omar
A1 Hernandez, Domingo
A1 Moreso, Francesc
A1 Melilli, Edoardo
A1 Juega, Javier
A1 de-Sousa, Erika
A1 Lopez-Sanchez, Paula
A1 Rodriguez-Ferrero, Maria Luisa
A1 Maruri-Kareaga, Naroa
A1 Navarro, Maria Dolores
A1 Valero, Rosalia
A1 Mazuecos, Maria Auxiliadora
A1 Llamas, Francisco
A1 Martin-Moreno, Paloma
A1 Fernandez-Garcia, Anton
A1 Espi, Jordi
A1 Jimenez, Carlos
A1 Ramos, Ana
A1 Gavela, Eva
A1 Pascual, Julio
A1 Portoles, Jose M
K1 Clinical outcomes
K1 Delayed graft function
K1 Donors after circulatory death
K1 Elderly donors
K1 Kidney transplantation
AB Spain has dramatically increased the number of controlled circulatory death donors (cDCD). The initial selection criteria for considering cDCD for kidney transplantation (KT) have been expanded progressively, with practically no limits in donor age during the last years. We aimed to analyze the early clinical outcomes using expanded (> 65 years) cDCD in comparison with standard ones. Observational multicenter study including 19 transplant centers in Spain. We performed a systematic inclusion in a central database of every KT from expanded cDCD at each participant unit from January-2012 to January-2017. Surgical procedures and immunosuppressive protocols were based on local practices. Data was analyzed in the central office using logistic and Cox regression or competitive-risk models for multivariate analysis. Median time of follow-up was 18.1 months. 561 KT were performed with kidneys from cDCD, 135 from donors older than 65 years. As expected, recipients from older cDCD were also older (65.8 (SD 8.8) vs 53.7 (SD 11.4) years; p  The use of kidneys from expanded cDCD is increasing for older and comorbid patients. Short-term graft outcomes are similar for expanded and standard cDCD, so they constitute a good-enough source of kidneys to improve the options of KT wait-listed patients.
PB BioMed Central
YR 2019
FD 2019-06-26
LK http://hdl.handle.net/10668/14182
UL http://hdl.handle.net/10668/14182
LA en
NO Pérez-Sáez MJ, Lafuente Covarrubias O, Hernández D, Moreso F, Melilli E, Juega J, et al. Early outcomes of kidney transplantation from elderly donors after circulatory death (GEODAS study). BMC Nephrol. 2019 Jun 26;20(1):233
NO This project was co-founded by Public Research Net REDINREN ISCIII 16/009/ 009, Renal Foundation FRIAT & Research Institute Segovia Arana-HU Puerta de Hierro. OLC, PLS and JMP belong to the latter institution (HU Puerta de Hierro). Funding was used for human resources: data manager and statistician support.
DS RISalud
RD Apr 7, 2025