TY - JOUR AU - Martinez-Font, Esther AU - Perez-Capo, Marina AU - Ramos, Rafael AU - Felipe, Irene AU - Garcias, Carmen AU - Luna, Pablo AU - Terrasa, Josefa AU - Martin-Broto, Javier AU - Vögler, Oliver AU - Alemany, Regina AU - Obrador-Hevia, Antonia PY - 2020 DO - 10.3390/cancers12092556 UR - http://hdl.handle.net/10668/4279 T2 - Cancers AB - The Wnt signaling pathway is an important cellular mechanism for regulating differentiation processes as well as cell cycle events, and different inhibitors of this pathway, for example, PRI-724, are showing promising results in clinical trials for... LA - en PB - MDPI KW - Soft tissue sarcoma KW - Wnt signaling KW - β-catenin KW - CDC25A KW - PRI-724 KW - Trabectedin KW - Sarcoma KW - Vía de señalización Wnt KW - Beta Catenina KW - Trabectedina KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Chemical Processes::Biochemical Processes::Signal Transduction::Wnt Signaling Pathway KW - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Antisense Elements (Genetics)::RNA, Antisense::RNA, Small Interfering KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Survival KW - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Histologic Type::Neoplasms, Glandular and Epithelial::Carcinoma::Adenocarcinoma KW - Medical Subject Headings::Information Science::Information Science::Information Storage and Retrieval::Databases as Topic::Databases, Factual::Databases, Genetic::Databases, Nucleic Acid KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Down-Regulation KW - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Pancreatic Neoplasms KW - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Physiological Processes::Growth and Development::Growth::Cell Growth Processes::Cell Proliferation KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Cycle KW - Medical Subject Headings::Chemicals and Drugs::Carbohydrates::Glycosides::Aminoglycosides::Anthracyclines::Daunorubicin::Doxorubicin KW - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Histologic Type::Neoplasms, Connective and Soft Tissue KW - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Endocrine Gland Neoplasms::Ovarian Neoplasms KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Cycle::Cell Cycle Checkpoints KW - Medical Subject Headings::Diseases::Neoplasms::Neoplastic Processes::Carcinogenesis KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Death KW - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Cytoskeletal Proteins::Catenins KW - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::RNA::RNA, Messenger TI - Impact of Wnt/β-Catenin Inhibition on Cell Proliferation through CDC25A Downregulation in Soft Tissue Sarcomas TY - research article ER -