TY - JOUR AU - López-Campos, José Luis AU - Carrasco Hernandez, Laura AU - Caballero Eraso, Candelaria PY - 2020 DO - 10.3390/jcm9082526 SN - 2077-0383 UR - https://hdl.handle.net/10668/27900 T2 - Journal of clinical medicine AB - Ever since the first studies, restoring proteinase imbalance in the lung has traditionally been considered as the main goal of alpha1 antitrypsin (AAT) replacement therapy. This strategy was therefore based on ensuring biochemical efficacy,... LA - en KW - alpha1 antitrypsin deficiency KW - augmentation therapy KW - rare diseases KW - replacement therapy TI - Implications of a Change of Paradigm in Alpha1 Antitrypsin Deficiency Augmentation Therapy: From Biochemical to Clinical Efficacy. TY - research article VL - 9 ER -