RT Journal Article
T1 Changes in Antimicrobial Resistance and Etiology of Blood Culture Isolates: Results of a Decade (2010-2019) of Surveillance in a Northern Region of Colombia.
A1 Robledo, Jaime
A1 Maldonado, Natalia
A1 Robledo, Carlos
A1 Ceballos Naranjo, Laura
A1 Hernández Galeano, Valentín
A1 Pino, Juan Jose
A1 Germen Antimicrobial Surveillance network, 
K1 antibacterial agents
K1 antimicrobial surveillance
K1 bacteremia
K1 drug resistance bacterial
AB Bloodstream infections (BSI) are important causes of morbidity and mortality worldwide. Antimicrobial surveillance is essential for identifying emerging resistance and generating empirical treatment guides, the purpose of this study is to analyze trends in antimicrobial susceptibility of BSI from 2010 to 2019 in healthcare institutions from Medellin and nearby towns in Colombia. A Whonet database was analyzed from the GERMEN antimicrobial surveillance network; frequency and antibiotic susceptibility trends were calculated on more frequent microorganisms using Mann Kendall and Sen's Slope Estimator Test. 61,299 isolates were included; the three microorganisms more frequent showed a significant increasing trend through time E. coli (Sen's Slope estimator = 0.7 p =  An upward trends was observed in more frequent microorganisms and resistance to third and fourth-generation cephalosporins for E. coli and K pneumoniae; in contrast, not increasing trends in antibiotic resistance was observed for P. aeruginosa and S. aureus. The essential role of AMR-surveillance programs is to point out and identify these trends, which should improve antibiotic resistance control.
SN 1178-6973
YR 2022
FD 2022-10-20
LK http://hdl.handle.net/10668/20462
UL http://hdl.handle.net/10668/20462
LA en
DS RISalud
RD Apr 12, 2025