RT Journal Article
T1 Non-acid reflux and sleep apnea: the importance of drug induced sleep endoscopy.
A1 O'Connor-Reina, Carlos
A1 Garcia, Jose Maria Ignacio
A1 Baptista, Peter
A1 Garcia-Iriarte, Maria Teresa
A1 Alba, Carlos Casado
A1 Perona, Monica
A1 Borrmann, Paz Francisca
A1 Alcala, Laura Rodriguez
A1 Plaza, Guillermo
K1 Continuous positive airway pressure
K1 Drug-induced sleep endoscopy
K1 Epiglottis
K1 Multichannel impedanciometry
K1 Nonacid reflux disease
K1 Obstructive sleep apnea
AB We present the first case of a patient with obstructive sleep apnea syndrome (OSA), where drug induced sleep endoscopy was helpful to suspect a non-acid reflux disease and showed an improvement in a swollen epiglottis after treatment. Patient ameliorated significantly his disease only with medical therapy. A 54-year-old man without significant anatomical findings with obstructive sleep apnea syndrome and non-acid gastroesophageal reflux disease (GERD) disease whose Apnea- hypopnea index (AHI) was significantly reduced with the intake of 500 mg of sodium alginate twice a day for 6 months. Conventional digestive tests such as esophagoscopy and simple- and double-channel 24-h pH-metry suggested mild GERD. Conventional proton-pump inhibitor treatment with pantoprazole (40 mg daily) was started without any improvement in his sleep. Multichannel intraluminal 24-h impedanciometry indicated the presence of severe pathological GER of gaseous origin. The patient's AHI decreased from 25.3 at baseline to 8 after treatment with sodium alginate. A drug-induced sleep endoscopy study showed the changes before and after this treatment and was helpful for the diagnosis. Thus, medical treatment can be a therapeutic option in some patients with OSA. Multichannel 24-h impedanciometry should be performed when nonacid GERD is suspected.
YR 2021
FD 2021-06-30
LK http://hdl.handle.net/10668/18063
UL http://hdl.handle.net/10668/18063
LA en
DS RISalud
RD Apr 10, 2025