%0 Journal Article
%A O'Connor-Reina, Carlos
%A Garcia, Jose Maria Ignacio
%A Baptista, Peter
%A Garcia-Iriarte, Maria Teresa
%A Alba, Carlos Casado
%A Perona, Monica
%A Borrmann, Paz Francisca
%A Alcala, Laura Rodriguez
%A Plaza, Guillermo
%T Non-acid reflux and sleep apnea: the importance of drug induced sleep endoscopy.
%D 2021
%U http://hdl.handle.net/10668/18063
%X We present the first case of a patient with obstructive sleep apnea syndrome (OSA), where drug induced sleep endoscopy was helpful to suspect a non-acid reflux disease and showed an improvement in a swollen epiglottis after treatment. Patient ameliorated significantly his disease only with medical therapy. A 54-year-old man without significant anatomical findings with obstructive sleep apnea syndrome and non-acid gastroesophageal reflux disease (GERD) disease whose Apnea- hypopnea index (AHI) was significantly reduced with the intake of 500 mg of sodium alginate twice a day for 6 months. Conventional digestive tests such as esophagoscopy and simple- and double-channel 24-h pH-metry suggested mild GERD. Conventional proton-pump inhibitor treatment with pantoprazole (40 mg daily) was started without any improvement in his sleep. Multichannel intraluminal 24-h impedanciometry indicated the presence of severe pathological GER of gaseous origin. The patient's AHI decreased from 25.3 at baseline to 8 after treatment with sodium alginate. A drug-induced sleep endoscopy study showed the changes before and after this treatment and was helpful for the diagnosis. Thus, medical treatment can be a therapeutic option in some patients with OSA. Multichannel 24-h impedanciometry should be performed when nonacid GERD is suspected.
%K Continuous positive airway pressure
%K Drug-induced sleep endoscopy
%K Epiglottis
%K Multichannel impedanciometry
%K Nonacid reflux disease
%K Obstructive sleep apnea
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