TY - JOUR AU - Pezzolla, Daniela AU - López-Beas, Javier AU - Lachaud, Christian C AU - Domínguez-Rodríguez, Alejandro AU - Smani, Tarik AU - Hmadcha, Abdelkrim AU - Soria, Bernat PY - 2015 DO - 10.1371/journal.pone.0119904 UR - http://hdl.handle.net/10668/2252 T2 - PloS ONE AB - Human embryonic stem cells (hESCs) retain the extraordinary capacity to differentiate into different cell types of an adult organism, including pancreatic β-cells. For this particular lineage, although a lot of effort has been made in the last ten... LA - en PB - Public Library of Science KW - Resveratrol KW - Stilbenes KW - Cell differentiation KW - Insulin KW - Insulin secretion KW - Endoderm KW - Diabetes mellitus KW - Pancreas KW - Immunofluorescence KW - Precursor cells KW - Diferenciación Celular KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation KW - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, Animal::Disease Models, Animal::Diabetes Mellitus, Experimental KW - Medical Subject Headings::Anatomy::Cells::Stem Cells::Pluripotent Stem Cells::Embryonic Stem Cells KW - Medical Subject Headings::Anatomy::Body Regions::Transplants::Heterografts KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Anatomy::Digestive System::Pancreas::Islets of Langerhans::Insulin-Secreting Cells KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice::Mice, Inbred Strains::Mice, Inbred NOD KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice::Mice, Mutant Strains::Mice, SCID KW - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Hydrocarbons, Cyclic::Hydrocarbons, Aromatic::Benzene Derivatives::Benzylidene Compounds::Stilbenes TI - Resveratrol ameliorates the maturation process of β-cell-like cells obtained from an optimized differentiation protocol of human embryonic stem cells. TY - research article ER -