RT Journal Article T1 Effectiveness of psychological and educational interventions for the prevention of depression in the workplace: A systematic review and meta-analysis. A1 Bellon, Juan Angel A1 Conejo-Ceron, Sonia A1 Cortes-Abela, Cayetana A1 Pena-Andreu, Jose Miguel A1 Garcia-Rodriguez, Antonio A1 Moreno-Peral, Patricia K1 Depression K1 Depressive disorder K1 Depressive symptom K1 Educational intervention K1 Effectiveness K1 Meta-analysis K1 Prevention K1 Primary prevention K1 Review K1 Systematic review K1 Workplace intervention AB Objectives Psychological and educational interventions for the prevention of depression have a small-to-moderate effect. However, little is known about their effectiveness in the workplace. We aimed to evaluate the effectiveness of such interventions through a systematic review and meta-analysis of randomized controlled trials (RCT). Methods We searched PubMed, PsycINFO, EMBASE, CENTRAL, CIS-DOC and Open Grey for RCT. Search was supplemented with manual searches of reference lists of relevant meta-analyses and trials. We included RCT that assessed either the incidence of depression or the reduction of depressive symptoms, which excluded participants with baseline depression. Measurements were required to have been made using validated instruments and participants recruited in the workplace. Independent evaluators selected studies, evaluated risk bias (Cochrane Collaboration's tool) and extracted from RCT. The combined OR was estimated using the fixed-effects model. Heterogeneity was measured by I 2and Cochrane's Q. Results Of the 1963 abstracts reviewed, 69 were selected for review in fulltext. Only three RCT met our inclusion criteria, representing 1246 workers from three different countries and continents. The combined odds ratio was 0.25 [95% confidence interval (CI) 0.11-0.60, P=0.002]; I 2=0% and Q=0.389 (P=0.823). The risk of bias was low in one RCT and moderate and high in the other two, respectively. Conclusion Psychological or educational interventions in the workplace may prevent depression, although the quality of evidence was low. PB Nordic Association of Occupational Safety and Health (NOROSH) YR 2018 FD 2018-11-30 LK http://hdl.handle.net/10668/13265 UL http://hdl.handle.net/10668/13265 LA en NO Bellón JÁ, Conejo-Cerón S, Cortés-Abela C, Pena-Andreu JM, García-Rodríguez A, Moreno-Peral P. Effectiveness of psychological and educational interventions for the prevention of depression in the workplace: A systematic review and meta-analysis. Scand J Work Environ Health. 2019 Jul 1;45(4):324-332 NO This study was supported by the Spanish Ministry of Health, the Institute of Health Carlos III, and the European Regional Development Fund «Una manera de hacer Europa» (grant FIS reference: PI12/02755) and the Andalusian Council of Health (grant reference: 0583/2012); as well as the Prevention and Health Promotion Research Network ‘redIAPP’ (RD16/0007). DS RISalud RD Sep 5, 2025