TY - JOUR AU - Martin-Serrano, Angela AU - Mayorga, Cristobalina AU - Barrionuevo, Esther AU - Perez, Natalia AU - Romano, Antonino AU - Moreno, Esther AU - Ariza, Adriana AU - Perez-Inestrosa, Ezequiel AU - Torres, Maria J AU - Montañez, Maria I PY - 2019 DO - 10.1016/j.jaci.2019.11.036 UR - http://hdl.handle.net/10668/14806 T2 - The Journal of allergy and clinical immunology AB - Like penicillins, cephalosporins are common antibiotics inducing adverse drug reactions mediated by specific immunologic mechanisms.1 The ‘‘hapten hypothesis’’ states that b-lactams can cause an allergic response only after binding covalently to... LA - en PB - Elsevier KW - Adolescent KW - Adult KW - Anti-bacterial agents KW - Cefaclor KW - Child KW - Child, preschool KW - Drug design KW - Drug hypersensitivity KW - Drug-related side effects and adverse reactions KW - Epitopes KW - Epitopes, B-Lymphocyte KW - Female KW - Humans KW - Immunoglobulin E KW - Male KW - Middle aged KW - Molecular structure KW - Protein dinding KW - Structure-activity relationship KW - Young adult TI - Design of an antigenic determinant of cefaclor: Chemical structure-IgE recognition relationship. TY - research article VL - 145 ER -