TY - JOUR AU - Lopez-Grueso, M J AU - Gonzalez-Ojeda, R AU - Requejo-Aguilar, R AU - McDonagh, B AU - Fuentes-Almagro, C A AU - Muntane, J AU - Barcena, J A AU - Padilla, C A PY - 2018 DO - 10.1016/j.redox.2018.11.007 UR - http://hdl.handle.net/10668/13418 T2 - Redox biology AB - The aim of the present study was to define the role of Trx and Grx on metabolic thiol redox regulation and identify their protein and metabolite targets. The hepatocarcinoma-derived HepG2 cell line under both normal and oxidative/nitrosative... LA - en PB - Elsevier KW - Glycolysis KW - NO synthase KW - Redox proteome KW - Redoxins KW - S-nitrosation KW - Thiol redox regulation KW - Cysteine KW - Energy metabolism KW - Gene expression regulation KW - Gene silencing KW - Glutaredoxins KW - Glycolysis KW - Hep G2 cells KW - Humans KW - Metabolic networks and pathways KW - Metabolomics KW - Oxidation-reduction KW - Proteome KW - Proteomics KW - Sulfhydryl compounds KW - Thioredoxins TI - Thioredoxin and glutaredoxin regulate metabolism through different multiplex thiol switches. TY - research article VL - 21 ER -