RT Generic
T1 Liquid Biopsy as a Tool for the Characterisation and Early Detection of the Field Cancerization Effect in Patients with Oral Cavity Carcinoma
A1 Perez-Ruiz, Elisabeth
A1 Gutierrez, Vanesa
A1 Munoz, Marta
A1 Oliver, Javier
A1 Sanchez, Marta
A1 Galvez-Carvajal, Laura
A1 Rueda-Dominguez, Antonio
A1 Barragan, Isabel
K1 oral cell carcinoma
K1 field cancerization
K1 liquid biopsy
K1 Squamous-cell carcinoma
K1 Locally advanced head
K1 Induction chemotherapy
K1 Acquired-resistance
K1 Tumor
K1 Exosomes
K1 Dna
K1 Plasma
K1 Heterogeneity
K1 Fluorouracil
AB Oral squamous cell carcinoma (OSCC) constitutes approximately 25% of all head and neck cancer, for which the consumption of tobacco and alcohol are the main associated risk factors. The field cancerization effect of OSCC is one of the main reasons for the poor survival rates associated with this disease. Despite some advances, its ccharacterization and early diagnosis continue to challenge modern oncology, and the goal of improving the prognosis remains to be achieved. Among new early diagnostic tools for OSCC that have been proposed, liquid biopsy appears to be an ideal candidate, as studies have shown that the analysis of blood and saliva provides promising data for the early detection of relapses or second tumours.
PB Mdpi
YR 2021
FD 2021-10-01
LK https://hdl.handle.net/10668/27020
UL https://hdl.handle.net/10668/27020
LA en
DS RISalud
RD Apr 11, 2025