TY  - JOUR
AU  - Nicoletti, Paola
AU  - Aithal, Guruprasad P
AU  - Chamberlain, Thomas C
AU  - Coulthard, Sally
AU  - Alshabeeb, Mohammad
AU  - Grove, Jane I
AU  - Andrade, Raul J
AU  - Bjornsson, Einar
AU  - Dillon, John F
AU  - Hallberg, Par
AU  - Lucena, M Isabel
AU  - Maitland-van der Zee, Anke H
AU  - Martin, Jennifer H
AU  - Molokhia, Mariam
AU  - Pirmohamed, Munir
AU  - Wadelius, Mia
AU  - Shen, Yufeng
AU  - Nelson, Matthew R
AU  - Daly, Ann K
PY  - 2018
DO  - 10.1002/cpt.1375
UR  - http://hdl.handle.net/10668/13436
T2  - Clinical pharmacology and therapeutics
AB  - Some patients prescribed flucloxacillin (~ 0.01%) develop drug-induced liver injury (DILI). HLA-B*57:01 is an established genetic risk factor for flucloxacillin DILI. To consolidate this finding, identify additional genetic factors, and assess...
LA  - en
PB  - Wiley
KW  - Anti-bacterial agents
KW  - Liver injury
KW  - Floxacillin
KW  - HLA-B antigens
KW  - Aged
KW  - Anti-bacterial agents
KW  - Chemical and drug induced liver injury
KW  - Female
KW  - Floxacillin
KW  - Genome-wide association study
KW  - Genotype
KW  - HLA-B antigens
KW  - Humans
KW  - Male
KW  - Middle aged
KW  - Penicillins
KW  - Polymorphism, single nucleotide
TI  - Drug-Induced Liver Injury due to Flucloxacillin: Relevance of Multiple Human Leukocyte Antigen Alleles.
TY  - research article
VL  - 106
ER  -