TY - JOUR AU - Valderrama-Carvajal, Alejandra AU - Irizar, Haritz AU - Gago, Belen AU - Jimenez-Urbieta, Haritz AU - Fuxe, Kjell AU - Rodriguez-Oroz, Maria C AU - Otaegui, David AU - Rivera, Alicia PY - 2018 DO - 10.1038/s41598-018-25604-4 UR - http://hdl.handle.net/10668/12440 T2 - Scientific reports AB - Morphine binding to opioid receptors, mainly to μ opioid receptor (MOR), induces alterations in intracellular pathways essential to the initial development of addiction. The activation of the dopamine D4 receptor (D4R), which is expressed in the... LA - en PB - Springer Nature KW - Analgesics KW - Benzamides KW - Dopamine agonists KW - Rats KW - Receptors KW - Analgesics, opioid KW - Animals KW - Benzamides KW - Caudate nucleus KW - Dopamine agonists KW - Gene expression KW - Male KW - Morphine KW - Piperazines KW - Putamen KW - Rats KW - Rats, sprague-dawley KW - Receptors, dopamine D4 KW - Receptors, opioid KW - Signal transduction KW - Transcriptome TI - Transcriptomic integration of D4R and MOR signaling in the rat caudate putamen. TY - research article VL - 8 ER -