RT Journal Article
T1 Toscana virus in Spain
A1 Sanbonmatsu-Gámez, Sara
A1 Pérez-Ruiz, Mercedes
A1 Collao, Ximena
A1 Sánchez-Seco, María Paz
A1 Morillas-Márquez, Francisco
A1 Rosa-Fraile, Manuel de la
A1 Navarro-Marí, José María
A1 Tenorio, Antonio
K1 Animales
K1 Anticuerpos Antivirales
K1 Femenino
K1 Humanos
K1 Inmunoglobulina G
K1 Insectos Vectores
K1 Masculino
K1 Phlebotomus
K1 Fiebre por Flebótomos
K1 Filogenia
K1 Prevalencia
K1 Virus de Nápoles de la Fiebre de la Mosca de los Arenales
K1 Análisis de Secuencia de ADN
K1 España
K1 Proteínas Virales
AB Toscana virus (TOSV, Phlebovirus, family Bunyaviridae) infection is one of the most prevalent arboviruses in Spain. Within the objectives of a multidisciplinary network, a study on the epidemiology of TOSV was conducted in Granada, in southern Spain. The overall seroprevalence rate was 24.9%, significantly increasing with age. TOSV was detected in 3 of 103 sandfly pools by viral culture or reverse transcription-polymerase chain reaction from a region of the L gene. Nucleotide sequence homology was 99%-100% in TOSV from vectors and patients and 80%-81% compared to the Italian strain ISS Phl.3. Sequencing of the N gene of TOSV isolates from patients and vectors indicated 87%-88% and 100% homology at the nucleotide and amino acid levels, respectively, compared to the Italian strain. These findings demonstrate the circulation of at least 2 different lineages of TOSV in the Mediterranean basin, the Italian lineage and the Spanish lineage.
PB U.S. National Center for Infectious Diseases
SN 1080-6040
YR 2005
FD 2005-11
LK http://hdl.handle.net/10668/608
UL http://hdl.handle.net/10668/608
LA en
NO Sanbonmatsu-Gámez S, Pérez-Ruiz M, Collao X, Sánchez-Seco MP, Morillas-Márquez F, Rosa-Fraile M de la, et al. Toscana virus in Spain.Emerg Infect Dis. 2005 Nov;11(11):1701-7.
NO Journal Article; Research Support, Non-U.S. Gov't;
DS RISalud
RD Apr 9, 2025