TY - JOUR AU - Gomez-Hurtado, Nieves AU - Dominguez-Rodriguez, Alejandro AU - Mateo, Philippe AU - Fernandez-Velasco, Maria AU - Val-Blasco, Almudena AU - Aizpun, Rafael AU - Sabourin, Jessica AU - Gomez, Ana Maria AU - Benitah, Jean-Pierre AU - Delgado, Carmen PY - 2017 DO - 10.1113/JP274030 UR - http://hdl.handle.net/10668/11050 T2 - The Journal of physiology AB - Leptin, is a 16 kDa pleiotropic peptide not only primarily secreted by adipocytes, but also produced by other tissues, including the heart. Controversy exists regarding the adverse and beneficial effects of leptin on the heart We analysed the effect... LA - en PB - Wiley-Blackwell Publishing Ltd. KW - heart failure KW - intracellular calcium KW - leptin KW - Action Potentials KW - Animals KW - Aortic Valve Stenosis KW - Calcium Signaling KW - Calcium-Calmodulin-Dependent Protein Kinase Type 2 KW - Cardiotonic Agents KW - Cells, Cultured KW - Kv Channel-Interacting Proteins KW - Leptin KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Myocytes, Cardiac KW - Ryanodine Receptor Calcium Release Channel KW - Shal Potassium Channels TI - Beneficial effects of leptin treatment in a setting of cardiac dysfunction induced by transverse aortic constriction in mouse. TY - research article VL - 595 ER -