TY - JOUR AU - Villatoro, Antonio J AU - Alcoholado, Cristina AU - Martin-Astorga, Maria Del Carmen AU - Rubio, Nuria AU - Blanco, Jeronimo AU - Garrido, Cristina Pilar AU - Becerra, Jose PY - 2022 DO - 10.1371/journal.pone.0264001 UR - http://hdl.handle.net/10668/20421 T2 - PloS one AB - The role played by certain domestic species such as dogs as a translational model in comparative oncology shows great interest to develop new therapeutic strategies in brain tumors. Gliomas are a therapeutic challenge that represents the most common... LA - en PB - Public Library of Science KW - Neoplasms KW - Brain KW - Lentivirus KW - Genetic therapy KW - Animals KW - Brain neoplasms KW - Cell line, tumor KW - Coculture techniques KW - Dogs KW - Ganciclovir KW - Genes KW - Genetic therapy KW - Glioblastoma KW - Herpes simplex KW - Humans KW - Lentivirus KW - Mesenchymal stem sell transplantation KW - Mesenchymal stem cells KW - Mice KW - Thymidine kinase KW - Transduction, genetic KW - Viral proteins KW - Xenograft model antitumor assays TI - Suicide gene therapy by canine mesenchymal stem cell transduced with thymidine kinase in a u-87 glioblastoma murine model: Secretory profile and antitumor activity TY - research article VL - 17 ER -