TY - JOUR AU - Garrido, Maria Antonia AU - Perea, Francisco AU - Vilchez, Jose Ramon AU - Rodriguez, Teresa AU - Anderson, Per AU - Garrido, Federico AU - Ruiz-Cabello, Francisco AU - Aptsiauri, Natalia PY - 2021 DO - 10.3390/cancers13205046 UR - https://hdl.handle.net/10668/26348 T2 - Cancers AB - Simple Summary: Loss of antigen presentation due to the altered expression of tumor HLA class I (HLA-I) molecules is a common mechanism of cancer immune escape. Loss of HLA-I haplotype, locus or a single allele due to genetic and chromosomal... LA - en PB - Mdpi KW - cancer immune escape KW - HLA class I KW - copy-neutral loss of heterozygosity (CN-LOH) KW - antigen presentation KW - beta2-microglobulin KW - cytotoxic T-cells KW - cancer immunotherapy KW - Human-leukocyte antigen KW - Altered phenotypes KW - Acquired-resistance KW - Melanoma-cells KW - Haplotype loss KW - Immune escape KW - Expression KW - Region KW - Heterozygosity KW - Identification TI - Copy Neutral LOH Affecting the Entire Chromosome 6 Is a Frequent Mechanism of HLA Class I Alterations in Cancer TY - research article VL - 13 ER -