RT Journal Article
T1 Giant cell arteritis: is the clinical spectrum of the disease changing?
A1 González-Gay, Miguel Á.
A1 Ortego-Jurado, Miguel
A1 Ercole, Liliana
A1 Ortego-Centeno, Norberto
K1 Giant-cell arteritis
K1 Polymyalgia rheumatic
K1 FDG-PET/CT
K1 Arteritis de células gigantes
K1 Polimialgia reumática
K1 Fluorodeoxyglucose F18
K1 Fluorodesoxiglucosa F18
K1 Positron Emission Tomography Computed Tomography
K1 Tomografía Computarizada por Tomografía de Emisión de Positrones
AB Background: Giant cell arteritis is a vasculitis of large and middle-sized arteries that affects patients aged over 50 years. It can show a typical clinical picture consisting of cranial manifestations but sometimes nonspecific symptoms and large-vessel involvement prevail. Prompt diagnosis and treatment is essential to avoid irreversible damage.Discussion: There has been an increasing knowledge on the occurrence of the disease without the typical cranial symptoms and its close relationship and overlap with polymyalgia rheumatica, and this may contribute to reduce the number of underdiagnosed patients. Although temporal artery biopsy is still the gold-standard and temporal artery ultrasonography is being widely used, newer imaging techniques (FDG-PET/TAC, MRI, CT) can be of valuable help to identify giant cell arteritis, in particular in those cases with a predominance of extracranial large-vessel manifestations.Conclusions: Giant cell arteritis is a more heterogeneous condition than previously thought. Awareness of all the potential clinical manifestations and judicious use of diagnostic tests may be an aid to avoid delayed detection and consequently ominous complications.
PB BioMed Central Ltd.
YR 2019
FD 2019-07-29
LK http://hdl.handle.net/10668/3158
UL http://hdl.handle.net/10668/3158
LA en
NO González-Gay MÁ, Ortego-Jurado M, Ercole L, Ortego-Centeno N. Giant cell arteritis: is the clinical spectrum of the disease changing? BMC Geriatr. 2019 Jul 29;19(1):200.
DS RISalud
RD Mar 13, 2025