TY  - JOUR
AU  - Jimenez-García, Manuel Pedro
AU  - Lucena-Cacace, Antonio
AU  - Otero-Albiol, Daniel
AU  - Carnero, Amancio
PY  - 2021
DO  - 10.1186/s13046-021-02048-9
UR  - http://hdl.handle.net/10668/4507
T2  - Journal of Experimental & Clinical Cancer Research
AB  - BackgroundSarcomas are a very heterogeneous group of tumors with intrinsic developmental programs derived from the cell of origin. This implies a functional hierarchy inside tumors governed by sarcoma stem cells. Therefore, genetic and/or epigenetic...
LA  - en
PB  - BioMed Central, Springer Nature
KW  - Wnt pathway
KW  - b-catenin
KW  - EMX
KW  - Sarcoma
KW  - Cancer
KW  - Cancer stem cells
KW  - Transcription factors
KW  - Phenotype
KW  - Regulatory genes
KW  - Cell lines
KW  - RNA
KW  - Vía de señalización Wnt
KW  - beta Catenina
KW  - Neoplasias
KW  - Células madre neoplásicas
KW  - Factores de transcripción
KW  - Fenotipo
KW  - Genes reguladores
KW  - Línea celular
KW  - ARN
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::DNA-Binding Proteins::Homeodomain Proteins
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Histologic Type::Neoplasms, Connective and Soft Tissue::Sarcoma
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Transcription Factors
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Gene Transfer Techniques::Transfection
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Chemical Processes::Biochemical Processes::Signal Transduction::Wnt Signaling Pathway
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Genes, Developmental::Genes, Homeobox
KW  - Medical Subject Headings::Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Computational Biology
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Epigenesis, Genetic
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Phenotype
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression::Transcription, Genetic
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Genes, Regulator
KW  - Medical Subject Headings::Anatomy::Cells::Stem Cells::Neoplastic Stem Cells
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplastic Processes::Carcinogenesis
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Cytoskeletal Proteins::Catenins
KW  - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::RNA::RNA, Messenger
KW  - Medical Subject Headings::Diseases::Neoplasms
TI  - Empty spiracles homeobox genes EMX1 and EMX2 regulate WNT pathway activation in sarcomagenesis
TY  - research article
ER  -