RT Journal Article
T1 Impact of Exposome Factors on Epidermal Barrier Function in Patients with Obstructive Sleep Apnea Syndrome.
A1 Romera-Vilchez, Maria
A1 Montero-Vilchez, Trinidad
A1 Herrero-Fernandez, Manuel
A1 Rodriguez-Pozo, Juan-Angel
A1 Jimenez-Galvez, Gonzalo
A1 Morales-Garcia, Concepcion
A1 Buendia-Eisman, Agustin
A1 Arias-Santiago, Salvador
K1 Obstructive Sleep Apnea
K1 anxiety
K1 diet
K1 exposome
K1 skin barrier
K1 sleep disorders
AB Exposome factors, such as sleep deprivation and diet, could affect skin barrier function. The objectives of this study are to compare skin barrier function between patients with Obstructive Sleep Apnea Syndrome (OSAS) and healthy individuals, and to evaluate the effect of other exposome factors on skin. A cross-sectional study was conducted. Patients with OSAS and healthy volunteers matched by age and sex were included. OSAS severity was assessed by the Apnea-Hypopnea Index (AHI). Validated questionnaires were used to assess diet, anxiety, depression, and psychological stress. Skin barrier function parameters including temperature, erythema, melanin, pH, transepidermal water loss (TEWL), and stratum corneum hydration (SCH) were measured on the volar forearm. A total of 86 participants were included, 56 patients with OSAS and 30 healthy volunteers. TEWL was higher in OSAS patients than in healthy individuals (8.01 vs. 8.68 g·m-2·h-1). Regarding disease severity, severe patients had higher TEWL values (9.31 vs. 8.46 vs. 7.08 g·m-2·h-1) compared to moderate and mild patients. Patients with OSAS had significantly lower sleep quality (11.89 vs. 6.47 Pittsburgh Sleep Quality Index score; p
PB MDPI AG
YR 2022
FD 2022-01-03
LK http://hdl.handle.net/10668/21017
UL http://hdl.handle.net/10668/21017
LA en
NO Romera-Vilchez M, Montero-Vilchez T, Herrero-Fernandez M, Rodriguez-Pozo JA, Jimenez-Galvez G, Morales-Garcia et al. Impact of Exposome Factors on Epidermal Barrier Function in Patients with Obstructive Sleep Apnea Syndrome. Int J Environ Res Public Health. 2022 Jan 7;19(2):659.
DS RISalud
RD Apr 9, 2025