RT Journal Article
T1 Sheep and goats raised in mixed flocks have diverse immune status around parturition.
A1 Hernandez-Castellano, Lorenzo E
A1 Moreno-Indias, Isabel
A1 Sanchez-Macias, Davinia
A1 Morales-delaNuez, Antonio
A1 Torres, Alexandr
A1 Argüello, Anastasio
A1 Castro, Noemi
K1 chitotriosidase
K1 complement system
K1 goat
K1 immunoglobulin
K1 sheep
AB Several physiological and metabolic changes take place in dairy ruminants around parturition (late pregnancy, parturition, and early lactation). Dairy species are genetically selected for their higher milk production compared with non-dairy species. This fact causes a constant stress that impairs the immune status of the animal, with consequences for its welfare and performance. In the present study, we assessed the immune status of high-yield dairy sheep and goats by quantifying IgG and IgM concentrations, as well as chitotriosidase (ChT) and complement system [total complement system (TC) and alternative complement pathway (AC)] activity in blood plasma around parturition. We also measured IgG and IgM concentrations and ChT activity in colostrum and milk during the first 40 d postpartum. The lowest blood IgG concentration was at parturition in both species. We detected no differences in blood IgG concentrations between species. Blood IgM concentrations were constant in both species throughout the study period. However, blood IgM concentrations were greater in sheep than in goats. Blood ChT activity was greater in goats than in sheep, and both species showed constant activity of this enzyme throughout the study period. We observed no differences in complement system (TC and AC) activity between sheep and goats. In addition, both TC and AC activity were constant in both species throughout the experiment. In general, IgG and IgM concentrations were greater in sheep colostrum than in goat colostrum, but these differences disappeared after d 4 (IgG) and d 3 (IgM) postpartum. In both species, the highest IgG and IgM concentrations were measured in colostrum, gradually decreasing during the first days postpartum. Chitotriosidase activity decreased in both species from colostrum to milk, although goats always showed greater ChT activity than sheep. Both sheep and goats seemed to be more susceptible to infectious diseases around parturition. As well, goats showed greater ChT activity in blood, colostrum, and milk than sheep. This fact may give these animals additional protection against parasite and fungal infections.
PB Elsevier
YR 2019
FD 2019-05-06
LK http://hdl.handle.net/10668/14197
UL http://hdl.handle.net/10668/14197
LA en
NO Hernández-Castellano LE, Moreno-Indias I, Sánchez-Macías D, Morales-delaNuez A, Torres A, Argüello A, Castro N. Sheep and goats raised in mixed flocks have diverse immune status around parturition. J Dairy Sci. 2019 Sep;102(9):8478-8485
NO Lorenzo E. Hernández-Castellano acknowledges financial support from the Formación del Profesorado Universitario (FPU) program (Ministry of Education,Spain) and from the Faculty of Science and Technology (Aarhus University, Denmark). Isabel Moreno-Indias was supported by the MS type I program (CP16/00163)from the Instituto de Salud Carlos III (Spain) and cofunded by Fondo Europeo de Desarrollo Regional (FEDER). Antonio Morales-delaNuez acknowledges funding from the Cabildo de Tenerife, under the identificationmark Tenerife 2030 (Program TF INNOVA 2016-2021), with MEDI and FDCAN funds. This experiment was funded by the grant AGL2006-08444/GAN from the Ministerio de Educación y Ciencia (Spain).
DS RISalud
RD Apr 6, 2025