RT Journal Article
T1 Influence of Mediterranean Diet Adherence and Physical Activity on Bone Health in Celiac Children on a Gluten-Free Diet.
A1 Nestares, Teresa
A1 Martin-Masot, Rafael
A1 de-Teresa, Carlos
A1 Bonillo, Rocio
A1 Maldonado, Jose
A1 Flor-Alemany, Marta
A1 Aparicio, Virginia A
K1 Mediterranean Diet
K1 Body composition
K1 Celiac disease
K1 Children
K1 Gluten-free diet
AB We aimed to assess the influence of the Mediterranean Diet adherence and physical activity (PA)(PA) on body composition, with a particular focus on bone health, in young patients with celiac disease (CD). The CD group (n = 59) included children with CD with a long (>18 months, n = 41) or recent (<18 months, n = 18) adherence to a gluten-free diet (GFD). The non-celiac group (n = 40) included non-celiac children. After adjusting for potential confounders, the CD group showed lower body weight (p = 0.034), lean mass (p = 0.003), bone mineral content (p = 0.006), and bone Z-score (p = 0.036) than non-celiac children, even when the model was further adjusted for adherence to a GFD for at least 18 months. Among CD children, spending greater time in vigorous physical activity was associated with higher lean mass (p = 0.020) and bone mineral density with evidence of statistical significance (p = 0.078) regardless of the time they followed a GFD. In addition, a greater Mediterranean Diet adherence was associated with a higher bone Z-score (p = 0.020). Moreover, lean mass was strongly associated with bone mineral density and independently explained 12% of its variability (p < 0.001). These findings suggest the importance of correctly monitoring lifestyle in children with CD regarding dietary habits and PA levels to improve lean mass and, consequently, bone quality in this population.
PB MDPI
YR 2021
FD 2021-05-13
LK http://hdl.handle.net/10668/17900
UL http://hdl.handle.net/10668/17900
LA en
NO Nestares T, Martín-Masot R, de Teresa C, Bonillo R, Maldonado J, Flor-Alemany M, et al. Influence of Mediterranean Diet Adherence and Physical Activity on Bone Health in Celiac Children on a Gluten-Free Diet. Nutrients. 2021 May 13;13(5):1636
NO This study was funded by the Regional Government of Andalusia, Excellence Research Project No P12-AGR-2581 and the Project from the University of Granada Ref. PP2017-PIP14. MFA was additionally funded by the Spanish Ministry of Education, Culture, and Sports (Grant number FPU17/03715).
DS RISalud
RD Apr 18, 2025