RT Journal Article
T1 Gut microbiota and aging-A focus on centenarians.
A1 Cӑtoi, Adriana Florinela
A1 Corina, Andreea
A1 Katsiki, Niki
A1 Vodnar, Dan Cristian
A1 Andreicut, Andra Diana
A1 Stoian, Anca Pantea
A1 Rizzo, Manfredi
A1 Perez-Martinez, Pablo
K1 Aging
K1 Centenarians
K1 Gut microbiota
K1 Prebiotics
K1 Probiotics
K1 Synbiotics
AB Gut microbiota (GM) is a dynamic organ throughout the lifespan. Aging is a complex process that comprises a plethora of mechanisms such as senescence, immunosenescence and inflammaging, representing important pathways of age-related diseases. GM structure could both influence and be influenced by aging occurring changes within the host. A unique category of long living individuals exists, namely centenarians that have the outstanding capacity to adapt to various challenges. Longevity seems to be associated with certain GM which, among other factors, might render individuals more resistant to age-related diseases and subsequently to long living. Diet, prebiotics, probiotics and synbiotics may contribute to longevity through GM modulating. Currently, the exact mechanisms of the association between GM and the host in relation with extended lifespan remain unknown and should be further investigated.
PB Elsevier
YR 2020
FD 2020-03-06
LK http://hdl.handle.net/10668/15237
UL http://hdl.handle.net/10668/15237
LA en
NO Cӑtoi AF, Corina A, Katsiki N, Vodnar DC, Andreicuț AD, Stoian AP, Rizzo M, Pérez-Martínez P. Gut microbiota and aging-A focus on centenarians. Biochim Biophys Acta Mol Basis Dis. 2020 Jul 1;1866(7):165765
DS RISalud
RD Apr 12, 2025