TY - JOUR AU - Gonzalez-Gil, Ines AU - Zian, Debora AU - Vazquez-Villa, Henar AU - Hernandez-Torres, Gloria AU - Martinez, R Fernando AU - Khiar-Fernandez, Nora AU - Rivera, Richard AU - Kihara, Yasuyuki AU - Devesa, Isabel AU - Mathivanan, Sakthikumar AU - Del Valle, Cristina Rosell AU - Zambrana-Infantes, Emma AU - Puigdomenech, Maria AU - Cincilla, Giovanni AU - Sanchez-Martinez, Melchor AU - Rodriguez de Fonseca, Fernando AU - Ferrer-Montiel, Antonio V AU - Chun, Jerold AU - Lopez-Vales, Ruben AU - Lopez-Rodriguez, Maria L AU - Ortega-Gutierrez, Silvia PY - 2019 DO - 10.1021/acs.jmedchem.9b01287 UR - http://hdl.handle.net/10668/14777 T2 - Journal of medicinal chemistry AB - Neuropathic pain (NP) is a complex chronic pain state with a prevalence of almost 10% in the general population. Pharmacological options for NP are limited and weakly effective, so there is a need to develop more efficacious NP attenuating drugs.... LA - en PB - American Chemical Society KW - Analgesics KW - Animals KW - Cell line KW - Cell movement KW - Cells, cultured KW - Analgesics KW - Animals KW - Cell Line KW - Cell movement KW - Cells, cultured KW - Drug discovery KW - Female KW - Humans KW - Hydrocarbons, aromatic KW - Mice, inbred C57BL KW - Models, molecular KW - Neuralgia KW - Pain perception KW - Rats, wistar KW - Receptors, lysophosphatidic acid KW - Sensory receptor cells TI - A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration. TY - research article VL - 63 ER -