RT Journal Article
T1 Management Strategies for Antipsychotic-Related Sexual Dysfunction: A Clinical Approach.
A1 Montejo, Angel L
A1 de Alarcón, Rubén
A1 Prieto, Nieves
A1 Acosta, José Mª
A1 Buch, Bárbara
A1 Montejo, Laura
K1 TESD
K1 anorgasmia
K1 antipsychotic
K1 erectile dysfunction
K1 management strategies
K1 orgasm retardation
K1 sexual dysfunction
K1 treatment
AB Antipsychotic medication can be often associated with sexual dysfunction (SD). Given its intimate nature, treatment emergent sexual dysfunction (TESD) remains underestimated in clinical practice. However, psychotic patients consider sexual issues as important as first rank psychotic symptoms, and their disenchantment with TESD can lead to important patient distress and treatment drop-out. In this paper, we detail some management strategies for TESD from a clinical perspective, ranging from prevention (carefully choosing an antipsychotic with a low rate of TESD) to possible pharmacological interventions aimed at improving patients' tolerability when TESD is present. The suggested recommendations include the following: prescribing either aripiprazole or another dopaminergic agonist as a first option antipsychotic or switching to it whenever possible. Whenever this is not possible, adjunctive treatment with aripiprazole seems to also be beneficial for reducing TESD. Some antipsychotics, like olanzapine, quetiapine, or ziprasidone, have less impact on sexual function than others, so they are an optimal second choice. Finally, a variety of useful strategies (such as the addition of sildenafil) are also described where the previous ones cannot be applied, although they may not yield as optimal results.
SN 2077-0383
YR 2021
FD 2021-01-15
LK http://hdl.handle.net/10668/17003
UL http://hdl.handle.net/10668/17003
LA en
DS RISalud
RD Mar 14, 2025