RT Journal Article
T1 Clinical Features and Outcomes of Paediatric Patients With Isolated Colonic Crohn Disease.
A1 Berger, Tal David
A1 Lee, Huey Miin
A1 Padmanaban, Lavenya Ramasamy
A1 Wine, Eytan
A1 Yerushalmy-Feler, Anat
A1 Hojsak, Iva
A1 Kazeka, Denis
A1 Serban, Daniela Elena
A1 Yogev, Dotan
A1 Ledder, Oren
A1 Lionetti, Paolo
A1 Scarallo, Luca
A1 Gasparetto, Marco
A1 Croft, Nicholas M
A1 Miele, Erasmo
A1 Staiano, Annamaria
A1 Meredith, Joseph
A1 Aloi, Marina
A1 Alvisi, Patrizia
A1 Urlep, Darja
A1 Weiss, Batia
A1 Malham, Mikkel
A1 Matar, Manar
A1 Navas-Lopez, Victor Manuel
A1 Romano, Claudio
A1 Dipasquale, Valeria
A1 Norsa, Lorenzo
A1 Kolho, Kaija-Leena
A1 Shamir, Raanan
A1 Shouval, Dror S
K1 Antibodies, Antineutrophil Cytoplasmic
K1 Antibodies, Fungal
K1 Child
K1 Colitis, Ulcerative
AB Adult studies suggest that patients with isolated colonic Crohn disease (L2 CD) exhibit unique characteristics differentiating them from patients with ileo-caecal (L1) CD and ulcerative colitis (UC). We aimed to characterize clinical features and outcomes of paediatric patients with L2. Retrospective data was collected through the Porto Inflammatory Bowel Disease group of the European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) on Paediatric patients with L2, L1 or UC at different time-points. Outcome measures included time to first flare, hospital admissions, initiation of anti-tumor necrosis factor-alpha (TNFα) drug, stricture and surgery. Three hundred patients were included: 102 L1, 94 L2 and 104 UC. Rates of hematochezia at presentation were 14.7%, 44.7% and 95.2%, while rates of fever were 12.7%, 26.6% and 2.9%, for patients with L1, L2 and UC, respectively (P  Significant differences are observed in the clinical presentation and outcomes of Paediatric patients with L2, compared to patients with L1 and UC.
PB Wiley
YR 2021
FD 2021-09-20
LK http://hdl.handle.net/10668/19858
UL http://hdl.handle.net/10668/19858
LA en
NO Berger TD, Lee HM, Padmanaban LR, Wine E, Yerushalmy-Feler A, Hojsak I, et al. Clinical Features and Outcomes of Paediatric Patients With Isolated Colonic Crohn Disease. J Pediatr Gastroenterol Nutr. 2022 Feb 1;74(2):258-266
DS RISalud
RD Apr 19, 2025