RT Journal Article
T1 Diet Quality Scores and Prediction of All-Cause, Cardiovascular and Cancer Mortality in a Pan-European Cohort Study.
A1 Lassale, Camille
A1 Gunter, Marc J
A1 Romaguera, Dora
A1 Peelen, Linda M
A1 Van der Schouw, Yvonne T
A1 Beulens, Joline W J
A1 Freisling, Heinz
A1 Muller, David C
A1 Ferrari, Pietro
A1 Huybrechts, Inge
A1 Fagherazzi, Guy
A1 Boutron-Ruault, Marie-Christine
A1 Affret, Aurélie
A1 Overvad, Kim
A1 Dahm, Christina C
A1 Olsen, Anja
A1 Roswall, Nina
A1 Tsilidis, Konstantinos K
A1 Katzke, Verena A
A1 Kühn, Tilman
A1 Buijsse, Brian
A1 Quirós, José-Ramón
A1 Sánchez-Cantalejo, Emilio
A1 Etxezarreta, Nerea
A1 Huerta, José María
A1 Barricarte, Aurelio
A1 Bonet, Catalina
A1 Khaw, Kay-Tee
A1 Key, Timothy J
A1 Trichopoulou, Antonia
A1 Bamia, Christina
A1 Lagiou, Pagona
A1 Palli, Domenico
A1 Agnoli, Claudia
A1 Tumino, Rosario
A1 Fasanelli, Francesca
A1 Panico, Salvatore
A1 Bueno-de-Mesquita, H Bas
A1 Boer, Jolanda M A
A1 Sonestedt, Emily
A1 Nilsson, Lena Maria
A1 Renström, Frida
A1 Weiderpass, Elisabete
A1 Skeie, Guri
A1 Lund, Eiliv
A1 Moons, Karel G M
A1 Riboli, Elio
A1 Tzoulaki, Ioanna
AB Scores of overall diet quality have received increasing attention in relation to disease aetiology; however, their value in risk prediction has been little examined. The objective was to assess and compare the association and predictive performance of 10 diet quality scores on 10-year risk of all-cause, CVD and cancer mortality in 451,256 healthy participants to the European Prospective Investigation into Cancer and Nutrition, followed-up for a median of 12.8y. All dietary scores studied showed significant inverse associations with all outcomes. The range of HRs (95% CI) in the top vs. lowest quartile of dietary scores in a composite model including non-invasive factors (age, sex, smoking, body mass index, education, physical activity and study centre) was 0.75 (0.72-0.79) to 0.88 (0.84-0.92) for all-cause, 0.76 (0.69-0.83) to 0.84 (0.76-0.92) for CVD and 0.78 (0.73-0.83) to 0.91 (0.85-0.97) for cancer mortality. Models with dietary scores alone showed low discrimination, but composite models also including age, sex and other non-invasive factors showed good discrimination and calibration, which varied little between different diet scores examined. Mean C-statistic of full models was 0.73, 0.80 and 0.71 for all-cause, CVD and cancer mortality. Dietary scores have poor predictive performance for 10-year mortality risk when used in isolation but display good predictive ability in combination with other non-invasive common risk factors.
YR 2016
FD 2016-07-13
LK http://hdl.handle.net/10668/10264
UL http://hdl.handle.net/10668/10264
LA en
DS RISalud
RD May 12, 2025