TY - JOUR AU - Heuser, Michael AU - Smith, B Douglas AU - Fiedler, Walter AU - Sekeres, Mikkael A AU - Montesinos, Pau AU - Leber, Brian AU - Merchant, Akil AU - Papayannidis, Cristina AU - Perez-Simon, Jose A AU - Hoang, Caroline J AU - O'Brien, Thomas AU - Ma, Weidong Wendy AU - Zeremski, Mirjana AU - O'Connell, Ashleigh AU - Chan, Geoffrey AU - Cortes, Jorge E PY - 2021 DO - 10.1007/s00277-021-04465-4 UR - http://hdl.handle.net/10668/17369 T2 - Annals of hematology AB - This analysis from the phase II BRIGHT AML 1003 trial reports the long-term efficacy and safety of glasdegib + low-dose cytarabine (LDAC) in patients with acute myeloid leukemia ineligible for intensive chemotherapy. The multicenter, open-label study... LA - en PB - Springer KW - Acute myeloid leukemia KW - Clinical trial KW - Glasdegib KW - Secondary acute myeloid leukemia KW - Aged KW - Aged, 80 and over KW - Antineoplastic Agents KW - Antineoplastic Combined Chemotherapy Protocols KW - Benzimidazoles KW - Cytarabine KW - Female KW - Humans KW - Leukemia, Myeloid, Acute KW - Male KW - Middle Aged KW - Neoplasms, Second Primary KW - Phenylurea Compounds KW - Survival Analysis KW - Treatment Outcome TI - Clinical benefit of glasdegib plus low-dose cytarabine in patients with de novo and secondary acute myeloid leukemia: long-term analysis of a phase II randomized trial. TY - research article VL - 100 ER -