RT Journal Article
T1 Management of bleeding following major trauma: a European guideline
A1 Spahn, Donat R
A1 Cerny, Vladimir
A1 Coats, Timothy J
A1 Duranteau, Jacques
A1 Fernández-Mondéjar, Enrique
A1 Gordini, Giovanni
A1 Stahel, Philip F
A1 Hunt, Beverley J
A1 Komadina, Radko
A1 Neugebauer, Edmund
A1 Ozier, Yves
A1 Riddez, Louis
A1 Schultz, Arthur
A1 Vincent, Jean-Louis
A1 Rossaint, Rolf
K1 Blood Substitutes
K1 Trastornos de la coagulación sanguínea
K1 Sustitutos sanguíneos
K1 Transfusión sanguínea
K1 Embolización terapéutica
K1 Tratamiento de urgencia
K1 Hemorragia
K1 Técnicas hemostáticas
K1 Humanos
K1 Resucitación
K1 Choque hemorrágico
K1 Factores de Tiempo
K1 Heridas y Traumatismos
K1 Cuestionarios
K1 Trastornos Somatosensoriales
K1 España
K1 Síndrome
K1 Traducciones
K1 Antifibrinolytic Agents
AB INTRODUCTIONEvidence-based recommendations can be made with respect to many aspects of the acute management of the bleeding trauma patient, which when implemented may lead to improved patient outcomes.METHODSThe multidisciplinary Task Force for Advanced Bleeding Care in Trauma was formed in 2005 with the aim of developing guidelines for the management of bleeding following severe injury. Recommendations were formulated using a nominal group process and the GRADE (Grading of Recommendations Assessment, Development, and Evaluation) hierarchy of evidence and were based on a systematic review of published literature.RESULTSKey recommendations include the following: The time elapsed between injury and operation should be minimised for patients in need of urgent surgical bleeding control, and patients presenting with haemorrhagic shock and an identified source of bleeding should undergo immediate surgical bleeding control unless initial resuscitation measures are successful. A damage control surgical approach is essential in the severely injured patient. Pelvic ring disruptions should be closed and stabilised, followed by appropriate angiographic embolisation or surgical bleeding control, including packing. Patients presenting with haemorrhagic shock and an unidentified source of bleeding should undergo immediate further assessment as appropriate using focused sonography, computed tomography, serum lactate, and/or base deficit measurements. This guideline also reviews appropriate physiological targets and suggested use and dosing of blood products, pharmacological agents, and coagulation factor replacement in the bleeding trauma patient.CONCLUSIONA multidisciplinary approach to the management of the bleeding trauma patient will help create circumstances in which optimal care can be provided. By their very nature, these guidelines reflect the current state-of-the-art and will need to be updated and revised as important new evidence becomes available.
PB BioMed Central
SN 1364-8535
YR 2007
FD 2007-02-13
LK http://hdl.handle.net/10668/715
UL http://hdl.handle.net/10668/715
LA en
NO Spahn DR, Cerny V, Coats TJ, Duranteau J, Fernández-Mondéjar E, Gordini G et al.Management of bleeding following major trauma: a European guideline.  Crit Care. 2007;11(1):R17.
NO Journal Article; Practice Guideline;
DS RISalud
RD Apr 10, 2025