TY  - JOUR
AU  - Alcina, Antonio
AU  - Fedetz, María
AU  - Ndagire, Dorothy
AU  - Fernández, Oscar
AU  - Leyva, Laura
AU  - Guerrero, Miguel
AU  - Abad-Grau, María M
AU  - Arnal, Carmen
AU  - Delgado, Concepción
AU  - Lucas, Miguel
AU  - Izquierdo, Guillermo
AU  - Matesanz, Fuencisla
PY  - 2009
DO  - 10.1371/journal.pone.0004137
UR  - http://hdl.handle.net/10668/1288
T2  - PloS One
AB  - BACKGROUND:IL-2 receptor (IL2R) alpha is the specific component of the high affinity IL2R system involved in the immune response and in the control of autoimmunity.METHODS AND RESULTS:Here we perform a replication and fine mapping of the IL2RA gene...
LA  - en
PB  - Public Library of Science
KW  - Alelos
KW  - Mapeo cromosómico
KW  - Diabetes mellitus tipo I
KW  - Predisposición genética a la enfermedad
KW  - Genotipo
KW  - Subunidad alfa del receptor de interleucina-2
KW  - Desequilibrio de ligamiento
KW  - Esclerosis múltiple
KW  - Polimorfismo de Nucleótido Simple
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Alleles
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Chromosome Mapping
KW  - Medical Subject Headings::Diseases::Endocrine System Diseases::Diabetes Mellitus::Diabetes Mellitus, Type 1
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genotype::Genetic Predisposition to Disease
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genotype
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Biological Markers::Antigens, Differentiation::Antigens, CD::Interleukin-2 Receptor alpha Subunit
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Linkage::Linkage Disequilibrium
KW  - Medical Subject Headings::Diseases::Immune System Diseases::Autoimmune Diseases::Autoimmune Diseases of the Nervous System::Demyelinating Autoimmune Diseases, CNS::Multiple Sclerosis
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism, Genetic::Polymorphism, Single Nucleotide
KW  - Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Young Adult
TI  - IL2RA/CD25 gene polymorphisms: uneven association with multiple sclerosis (MS) and type 1 diabetes (T1D).
TY  - research article
ER  -