TY - JOUR AU - Carmona, Andres AU - Guerrero, Fatima AU - Buendia, Paula AU - Obrero, Teresa AU - Aljama, Pedro AU - Carracedo, Julia PY - 2017 DO - 10.3389/fphys.2017.00666 SN - 1664-042X UR - http://hdl.handle.net/10668/19241 T2 - Frontiers in physiology AB - Cardiovascular disease is a major cause of mortality in chronic kidney disease patients. Indoxyl sulfate (IS) is a typical protein-bound uremic toxin that cannot be effectively cleared by conventional dialysis. Increased IS is associated with the... LA - en PB - Frontiers Research Foundation KW - Indoxyl sulfate KW - Endothelial microvesicles KW - Endothelial progenitor cells KW - Endothelial dysfunction KW - MiRNAs KW - Chronic kidney-disease KW - Proximal tubular cells KW - Chronic-renal-failure KW - Oxidative stress KW - Circulating microparticles KW - Extracellular vesicles KW - Vascular repair KW - Uremic toxins KW - Expression KW - Proliferation KW - Tumor suppressor protein p53 KW - Uremic toxins KW - Endothelial progenitor cells KW - Cardiovascular diseases KW - Renal insufficiency, chronic KW - Stem cells KW - Vascular diseases KW - Apoptosis TI - Microvesicles Derived from Indoxyl Sulfate Treated Endothelial Cells Induce Endothelial Progenitor Cells Dysfunction TY - research article VL - 8 ER -