RT Journal Article T1 Thermo-Sensitive Nanomaterials: Recent Advance in Synthesis and Biomedical Applications. A1 Sánchez-Moreno, Paola A1 de Vicente, Juan A1 Nardecchia, Stefania A1 Marchal, Juan A A1 Boulaiz, Houria K1 LCST K1 PNIPAm K1 thermo-responsive polymers K1 thermo-sensitive nanomaterials K1 thermochromism AB Progress in nanotechnology has enabled us to open many new fronts in biomedical research by exploiting the peculiar properties of materials at the nanoscale. The thermal sensitivity of certain materials is a highly valuable property because it can be exploited in many promising applications, such as thermo-sensitive drug or gene delivery systems, thermotherapy, thermal biosensors, imaging, and diagnosis. This review focuses on recent advances in thermo-sensitive nanomaterials of interest in biomedical applications. We provide an overview of the different kinds of thermoresponsive nanomaterials, discussing their potential and the physical mechanisms behind their thermal response. We thoroughly review their applications in biomedicine and finally discuss the current challenges and future perspectives of thermal therapies. SN 2079-4991 YR 2018 FD 2018-11-13 LK https://hdl.handle.net/10668/28126 UL https://hdl.handle.net/10668/28126 LA en DS RISalud RD Apr 17, 2025