RT Journal Article
T1 Management of bleeding and coagulopathy following major trauma: an updated European guideline.
A1 Spahn, Donat R
A1 Bouillon, Bertil
A1 Cerny, Vladimir
A1 Coats, Timothy J
A1 Duranteau, Jacques
A1 Fernández-Mondéjar, Enrique
A1 Filipescu, Daniela
A1 Hunt, Beverley J
A1 Komadina, Radko
A1 Nardi, Giuseppe
A1 Neugebauer, Edmund
A1 Ozier, Yves
A1 Riddez, Louis
A1 Schultz, Arthur
A1 Vincent, Jean-Louis
A1 Rossaint, Rolf
K1 Trastornos de la coagulación sanguínea
K1 Sustitutos Sanguíneos
K1 Transfusión Sanguínea
K1 Tratamiento de Urgencia
K1 Hemorragia
K1 Resucitación
K1 Choque Hemorrágico
K1 Factores de Tiempo
K1 Heridas y Traumatismos
K1 Humanos
K1 Antifibrinolíticos
K1 Técnicas hemostáticas
K1 Embolización terapéutica
AB INTRODUCTION: Evidence-based recommendations are needed to guide the acute management of the bleeding trauma patient. When these recommendations are implemented patient outcomes may be improved. METHODS: The multidisciplinary Task Force for Advanced Bleeding Care in Trauma was formed in 2005 with the aim of developing a guideline for the management of bleeding following severe injury. This document represents an updated version of the guideline published by the group in 2007 and updated in 2010. Recommendations were formulated using a nominal group process, the Grading of Recommendations Assessment, Development and Evaluation (GRADE) hierarchy of evidence and based on a systematic review of published literature. RESULTS: Key changes encompassed in this version of the guideline include new recommendations on the appropriate use of vasopressors and inotropic agents, and reflect an awareness of the growing number of patients in the population at large treated with antiplatelet agents and/or oral anticoagulants. The current guideline also includes recommendations and a discussion of thromboprophylactic strategies for all patients following traumatic injury. The most significant addition is a new section that discusses the need for every institution to develop, implement and adhere to an evidence-based clinical protocol to manage traumatically injured patients. The remaining recommendations have been re-evaluated and graded based on literature published since the last edition of the guideline. Consideration was also given to changes in clinical practice that have taken place during this time period as a result of both new evidence and changes in the general availability of relevant agents and technologies. CONCLUSIONS: A comprehensive, multidisciplinary approach to trauma care and mechanisms with which to ensure that established protocols are consistently implemented will ensure a uniform and high standard of care across Europe and beyond.
PB BioMed Central
SN 1364-8535
YR 2013
FD 2013-04-19
LK http://hdl.handle.net/10668/1495
UL http://hdl.handle.net/10668/1495
LA en
NO Spahn DR, Bouillon B, Cerny V, Coats TJ, Duranteau J, Fernández-Mondéjar E, et al. Management of bleeding and coagulopathy following major trauma: an updated European guideline. Crit Care. 2013 17(2):R76
NO JOURNAL ARTICLE; Practice Guideline
DS RISalud
RD Apr 6, 2025