TY - JOUR AU - Ortiz-Fernandez, Lourdes AU - Carmona, Francisco David AU - Lopez-Mejias, Raquel AU - Gonzalez-Escribano, Maria Francisca AU - Lyons, Paul A AU - Morgan, Ann W AU - Sawalha, Amr H AU - Merkel, Peter A AU - Smith, Kenneth G C AU - Gonzalez-Gay, Miguel A AU - Martin, Javier PY - 2018 DO - 10.1136/annrheumdis-2017-212372 UR - http://hdl.handle.net/10668/12055 T2 - Annals of the rheumatic diseases AB - Systemic vasculitides represent a heterogeneous group of rare complex diseases of the blood vessels with a poorly understood aetiology. To investigate the shared genetic component underlying their predisposition, we performed the first cross-phenotype... LA - en PB - BMJ Group KW - autoantibodies KW - outcomes research KW - systemic sclerosis KW - Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis KW - Case-Control Studies KW - Epigenesis, Genetic KW - Female KW - Genetic Loci KW - Genetic Predisposition to Disease KW - Giant Cell Arteritis KW - HLA-DQ Antigens KW - HLA-DQ beta-Chains KW - Humans KW - Jumonji Domain-Containing Histone Demethylases KW - Linkage Disequilibrium KW - Male KW - Phenotype KW - Polymorphism, Single Nucleotide KW - Protein Array Analysis KW - Systemic Vasculitis KW - Takayasu Arteritis TI - Cross-phenotype analysis of Immunochip data identifies KDM4C as a relevant locus for the development of systemic vasculitis. TY - research article VL - 77 ER -