TY - JOUR AU - Borroto-Escuela, Dasiel O. AU - Ferraro, Luca AU - Narvaez, Manuel AU - Tanganelli, Sergio AU - Beggiato, Sarah AU - Liu, Fang AU - Rivera, Alicia AU - Fuxe, Kjell PY - 2020 DO - 10.3390/cells9051077 UR - http://hdl.handle.net/10668/3840 T2 - Cells AB - In the 1980s and 1990s, the concept was introduced that molecular integration in the Central Nervous System could develop through allosteric receptor-receptor interactions in heteroreceptor complexes presents in neurons. A number of adenosine-dopamine... LA - en PB - MDPI KW - Adenosine receptors KW - A2A-D2 heteroreceptor complexes KW - Schizophrenia KW - Brain KW - Novel pharmacology KW - Heterobivalent drugs KW - Sigma 1 receptor KW - Receptor de adenosina A2A KW - Esquizofrenia KW - Encéfalo KW - Farmacología KW - Proteínas del núcleo viral KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, Purinergic::Receptors, Purinergic P1::Receptors, Adenosine A2::Receptor, Adenosine A2A KW - Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain KW - Medical Subject Headings::Anatomy::Nervous System::Central Nervous System KW - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amines::Biogenic Amines::Biogenic Monoamines::Catecholamines::Dopamine KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Anatomy::Nervous System::Neurons KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, G-Protein-Coupled::Receptors, Catecholamine::Receptors, Dopamine::Receptors, Dopamine D2 KW - Medical Subject Headings::Psychiatry and Psychology::Mental Disorders::Schizophrenia and Disorders with Psychotic Features::Schizophrenia TI - Multiple Adenosine-Dopamine (A2A-D2 Like) Heteroreceptor Complexes in the Brain and Their Role in Schizophrenia TY - review article ER -