RT Journal Article T1 Ablation with zero-fluoroscopy of premature ventricular complexes from aortic sinus cusps: A single-center experience A1 Sanchez-Millan, Pablo J. A1 Gutierrez-Ballesteros, Guillermo A1 Molina-Lerma, Manuel A1 Macias-Ruiz, Rosa A1 Jimenez-Jaimez, Juan A1 Tercedor, Luis A1 Alvarez, Miguel K1 aortic sinus cusp ventricular arrhythmias K1 intracardiac echocardiography K1 zero-fluoroscopy K1 Radiofrequency catheter K1 Image integration K1 Arrhythmias K1 Angiography K1 Injuries K1 Safety K1 Root AB Background: Catheter ablation of premature ventricular complexes from aortic sinus cusps (ASC-PVC) is a complex procedure that conventionally requires coronary catheterization (CC) to localize coronary artery ostium (CAO). Little published information is available on the mapping and ablation with zero-fluoroscopy (ZF) of ASC-PVC. The aim of the study was to determine the efficacy and safety of ASC-PVC ablation with a ZF approach guided by 3D intracardiac echocardiography integration in the electroanatomical mapping system (ICE 3D-EAM).Methods: This observational study included one patient cohort treated conventionally and another treated with ICE 3D-EAM-guided ZF ablation. Clinical, efficacy, and safety outcomes were evaluated acutely and at 3 months follow-up.Results: The study included 21 patients with ASC-PVC: 10 in the ZF group (age 49 +/- 16 years, 60% males) and 11 in the control group (age 47 +/- 15 years, 27% males). Fluoroscopy was not required for any patient in the ZF group. Acute success was obtained in 80% of the ZF group vs 55% of the control group (P = .36). The recurrence rate was 30% in the ZF group vs 27% in the control group (P = 1). One nonsevere complication was observed in the ZF group (P = .48).Conclusions: ZF catheter ablation of ASC-PVC guided by ICE 3D-EAM is feasible, effective, and safe. PB Wiley SN 1880-4276 YR 2021 FD 2021-10-03 LK https://hdl.handle.net/10668/24960 UL https://hdl.handle.net/10668/24960 LA en DS RISalud RD Apr 7, 2025