RT Journal Article T1 Whither Magnetic Hyperthermia? A Tentative Roadmap. A1 Rubia-Rodriguez, Irene A1 Santana-Otero, Antonio A1 Spassov, Simo A1 Tombacz, Etelka A1 Johansson, Christer A1 De La Presa, Patricia A1 Teran, Francisco J A1 Del Puerto Morales, Maria A1 Veintemillas-Verdaguer, Sabino A1 Thanh, Nguyen T K A1 Besenhard, Maximilian O A1 Wilhelm, Claire A1 Gazeau, Florence A1 Harmer, Quentin A1 Mayes, Eric A1 Manshian, Bella B A1 Soenen, Stefaan J A1 Gu, Yuanyu A1 Millan, Angel A1 Efthimiadou, Eleni K A1 Gaudet, Jeff A1 Goodwill, Patrick A1 Mansfield, James A1 Steinhoff, Uwe A1 Wells, James A1 Wiekhorst, Frank A1 Ortega, Daniel K1 Cancer K1 Hysteresis losses K1 Magnetic hyperthermia K1 Magnetic nanoparticles K1 Magnetic particle imaging K1 Nanoparticles synthesis K1 Nanotoxicity K1 Standardization K1 Theranostics K1 Thermometry AB The scientific community has made great efforts in advancing magnetic hyperthermia for the last two decades after going through a sizeable research lapse from its establishment. All the progress made in various topics ranging from nanoparticle synthesis to biocompatibilization and in vivo testing have been seeking to push the forefront towards some new clinical trials. As many, they did not go at the expected pace. Today, fruitful international cooperation and the wisdom gain after a careful analysis of the lessons learned from seminal clinical trials allow us to have a future with better guarantees for a more definitive takeoff of this genuine nanotherapy against cancer. Deliberately giving prominence to a number of critical aspects, this opinion review offers a blend of state-of-the-art hints and glimpses into the future of the therapy, considering the expected evolution of science and technology behind magnetic hyperthermia. PB MDPI SN 1996-1944 YR 2021 FD 2021-01-25 LK http://hdl.handle.net/10668/17111 UL http://hdl.handle.net/10668/17111 LA en NO Rubia-Rodríguez I, Santana-Otero A, Spassov S, Tombácz E, Johansson C, De La Presa P, et al. Whither Magnetic Hyperthermia? A Tentative Roadmap. Materials (Basel). 2021 Feb 3;14(4):706 NO Stefanos Mourdikoudis, Liudmyla Storozhuk, Asterios Gavriilidis are thankedfor their useful discussions. D.O., A.S.-O. and I.R.-R. gratefully acknowledge the support of NVIDIA Corporation through the GPU Grant Program with the donation of the Quadro P6000 GPU used for this research. DS RISalud RD Apr 7, 2025