TY  - JOUR
AU  - Mazzotta, Sarah
AU  - Berastegui-Cabrera, Judith
AU  - Vega-Holm, Margarita
AU  - Garcia-Lozano, Maria Del Rosario
AU  - Carretero-Ledesma, Marta
AU  - Aiello, Francesca
AU  - Vega-Perez, Jose Manuel
AU  - Pachon, Jeronimo
AU  - Iglesias-Guerra, Fernando
AU  - Sanchez-Cespedes, Javier
PY  - 2021
DO  - 10.1016/j.bioorg.2021.105095
UR  - http://hdl.handle.net/10668/18047
T2  - Bioorganic chemistry
AB  - Nowadays there is not an effective drug for the treatment of infections caused by human adenovirus (HAdV) which supposes a clinical challenge, especially for paediatric and immunosuppressed patients. Here, we describe the design, synthesis and...
LA  - en
PB  - Academic Press
KW  - Adenovirus
KW  - Aminoalcohol
KW  - Antiviral drugs
KW  - Carbamate
KW  - Ester
KW  - Triazole
KW  - Urea
KW  - Adenoviridae
KW  - Antiviral Agents
KW  - Cell Line
KW  - Cell Survival
KW  - Dose-Response Relationship, Drug
KW  - Drug Design
KW  - Humans
KW  - Microbial Sensitivity Tests
KW  - Molecular Structure
KW  - Propanolamines
KW  - Structure-Activity Relationship
TI  - Design, synthesis and in vitro biological evaluation of a novel class of anti-adenovirus agents based on 3-amino-1,2-propanediol.
TY  - research article
VL  - 114
ER  -