TY  - JOUR
AU  - Blanco, Ignacio
AU  - Bueno, Patricia
AU  - Diego, Isidro
AU  - Pérez-Holanda, Sergio
AU  - Lara, Beatriz
AU  - Casas-Maldonado, Francisco
AU  - Esquinas, Cristina
AU  - Miravitlles, Marc
PY  - 2017
DO  - 10.2147/COPD.S137852
UR  - http://hdl.handle.net/10668/11347
T2  - International journal of chronic obstructive pulmonary disease
AB  - The alpha-1 antitrypsin (AAT) haplotype Pi*S, when inherited along with the Pi*Z haplotype to form a Pi*SZ genotype, can be associated with pulmonary emphysema in regular smokers, and less frequently with liver disease, panniculitis, and systemic...
LA  - en
KW  - SERPINA1
KW  - SZ genotype
KW  - alpha-1 antitrypsin deficiency
KW  - genetic epidemiology
KW  - geographic information system
KW  - inverse distance-weighted interpolation
KW  - protease inhibitor
KW  - Gene Frequency
KW  - Genetic Predisposition to Disease
KW  - Global Health
KW  - Haplotypes
KW  - Heterozygote
KW  - Humans
KW  - Liver Diseases
KW  - Molecular Epidemiology
KW  - Multivariate Analysis
KW  - Panniculitis
KW  - Phenotype
KW  - Prevalence
KW  - Pulmonary Emphysema
KW  - Systemic Vasculitis
KW  - alpha 1-Antitrypsin
KW  - alpha 1-Antitrypsin Deficiency
TI  - Alpha-1 antitrypsin Pi*SZ genotype: estimated prevalence and number of SZ subjects worldwide.
TY  - research article
VL  - 12
ER  -