TY  - JOUR
AU  - Abakir, Abdulkadir
AU  - Giles, Tom C
AU  - Cristini, Agnese
AU  - Foster, Jeremy M
AU  - Dai, Nan
AU  - Starczak, Marta
AU  - Rubio-Roldan, Alejandro
AU  - Li, Miaomiao
AU  - Eleftheriou, Maria
AU  - Crutchley, James
AU  - Flatt, Luke
AU  - Young, Lorraine
AU  - Gaffney, Daniel J
AU  - Denning, Chris
AU  - Dalhus, Bjørn
AU  - Emes, Richard D
AU  - Gackowski, Daniel
AU  - Corrêa, Ivan R
AU  - Garcia-Perez, Jose L
AU  - Klungland, Arne
AU  - Gromak, Natalia
AU  - Ruzov, Alexey
PY  - 2019
DO  - 10.1038/s41588-019-0549-x
UR  - http://hdl.handle.net/10668/14837
T2  - Nature genetics
AB  - R-loops are nucleic acid structures formed by an RNA:DNA hybrid and unpaired single-stranded DNA that represent a source of genomic instability in mammalian cells1-4. Here we show that N6-methyladenosine (m6A) modification, contributing to different...
LA  - en
KW  - Adenosine
KW  - Animals
KW  - DNA
KW  - DNA Damage
KW  - Genomic Instability
KW  - Humans
KW  - Mice
KW  - Mice, Knockout
KW  - Mitosis
KW  - Pluripotent Stem Cells
KW  - RNA
KW  - RNA Stability
KW  - RNA, Messenger
KW  - RNA-Binding Proteins
TI  - N6-methyladenosine regulates the stability of RNA:DNA hybrids in human cells.
TY  - research article
VL  - 52
ER  -