TY - JOUR AU - Haugaard-Kedström, Linda M AU - Clemmensen, Louise S AU - Sereikaite, Vita AU - Jin, Zeyu AU - Fernandes, Eduardo F A AU - Wind, Bianca AU - Abalde-Gil, Flor AU - Daberger, Jan AU - Vistrup-Parry, Maria AU - Aguilar-Morante, Diana AU - Leblanc, Raphael AU - Egea-Jimenez, Antonio L AU - Albrigtsen, Marte AU - Jensen, Kamilla E AU - Jensen, Thomas M T AU - Ivarsson, Ylva AU - Vincentelli, Renaud AU - Hamerlik, Petra AU - Andersen, Jeanette Hammer AU - Zimmermann, Pascale AU - Lee, Weontae AU - Strømgaard, Kristian PY - 2021 DO - 10.1021/acs.jmedchem.0c00382 UR - https://hdl.handle.net/10668/26203 T2 - Journal of medicinal chemistry AB - Despite the recent advances in cancer therapeutics, highly aggressive cancer forms, such as glioblastoma (GBM), still have very low survival rates. The intracellular scaffold protein syntenin, comprising two postsynaptic density... LA - en KW - Animals KW - Antineoplastic Agents KW - Brain Neoplasms KW - Cell Line, Tumor KW - Drug Delivery Systems KW - Glioblastoma KW - High-Throughput Screening Assays KW - Humans KW - Ligands KW - Mice KW - Microsomes KW - Models, Molecular KW - Mutation KW - Peptides KW - Protein Binding KW - Syntenins KW - X-Ray Diffraction KW - Xenograft Model Antitumor Assays TI - A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma. TY - research article VL - 64 ER -