TY - JOUR AU - Martin-Broto, Javier AU - Hindi, Nadia AU - Grignani, Giovanni AU - Martinez-Trufero, Javier AU - Redondo, Andres AU - Valverde, Claudia AU - Stacchiotti, Silvia AU - Lopez-Pousa, Antonio AU - D'Ambrosio, Lorenzo AU - Gutierrez, Antonio AU - Perez-Vega, Herminia AU - Encinas-Tobajas, Victor AU - de Alava, Enrique AU - Collini, Paola AU - Peña-Chilet, Maria AU - Dopazo, Joaquin AU - Carrasco-Garcia, Irene AU - Lopez-Alvarez, Maria AU - Moura, David S AU - Lopez-Martin, Jose A PY - 2020 DO - 10.1136/jitc-2020-001561 UR - http://hdl.handle.net/10668/16624 T2 - Journal for immunotherapy of cancer AB - Sarcomas exhibit low expression of factors related to immune response, which could explain the modest activity of PD-1 inhibitors. A potential strategy to convert a cold into an inflamed microenvironment lies on a combination therapy. As tumor... LA - en PB - BMJ Group KW - clinical trials as topic KW - immunotherapy KW - sarcoma KW - translational medical research KW - Adult KW - Aged KW - Antineoplastic Agents, Immunological KW - Female KW - Humans KW - Male KW - Middle Aged KW - Nivolumab KW - Sarcoma KW - Sunitinib KW - Young Adult TI - Nivolumab and sunitinib combination in advanced soft tissue sarcomas: a multicenter, single-arm, phase Ib/II trial. TY - research article VL - 8 ER -