TY - JOUR AU - Marques, Miriam AU - Tranchant, Robin AU - Risa-Ebri, Blanca AU - Suarez-Solis, Maria L AU - Fernandez, Luis C AU - Carrillo-de-Santa-Pau, Enrique AU - Del Pozo, Natalia AU - Martinez de Villarreal, Jaime AU - Meiller, Clement AU - Allory, Yves AU - Blum, Yuna AU - Pirker, Christine AU - Hegedus, Balazs AU - Barry, Simon T AU - Carnero, Amancio AU - Berger, Walter AU - Jean, Didier AU - Real, Francisco X PY - 2020 DO - 10.1158/0008-5472.CAN-19-1633 UR - http://hdl.handle.net/10668/14929 T2 - Cancer research AB - Among malignant mesotheliomas (MM), the sarcomatoid subtype is associated with higher chemoresistance and worst survival. Due to its low incidence, there has been little progress in the knowledge of the molecular mechanisms associated with sarcomatoid... LA - en PB - American Association for Cancer Research KW - Aniline Compounds KW - Benzimidazoles KW - Chromones KW - Epithelium KW - Lung Neoplasms KW - Mesothelioma KW - Peritoneum KW - Pleura KW - Animals KW - Antineoplastic Combined Chemotherapy Protocols KW - Cell Proliferation KW - Class I Phosphatidylinositol 3-Kinases KW - Disease Models, Animal KW - Female KW - Gene Knock-In Techniques KW - Humans KW - Mesothelioma, Malignant KW - Mice KW - Mice, Knockout KW - Mitogen-Activated Protein Kinase Kinases KW - Molecular Targeted Therapy KW - PTEN Phosphohydrolase KW - Peritoneal Neoplasms KW - Pleural Neoplasms KW - Primary Cell Culture KW - Prognosis KW - Protein Kinase Inhibitors KW - Tumor Suppressor Protein p53 TI - Combined MEK and PI3K/p110β Inhibition as a Novel Targeted Therapy for Malignant Mesothelioma Displaying Sarcomatoid Features. TY - research article VL - 80 ER -