TY  - JOUR
AU  - Sessa, Gaetana
AU  - Gómez-González, Belén
AU  - Silva, Sonia
AU  - Pérez-Calero, Carmen
AU  - Beaurepere, Romane
AU  - Barroso, Sonia
AU  - Martineau, Sylvain
AU  - Martin, Charlotte
AU  - Ehlén, Åsa
AU  - Martínez, Juan S
AU  - Lombard, Bérangère
AU  - Loew, Damarys
AU  - Vagner, Stephan
AU  - Aguilera, Andrés
AU  - Carreira, Aura
PY  - 2021
DO  - 10.15252/embj.2020106018
UR  - http://hdl.handle.net/10668/17243
T2  - The EMBO journal
AB  - The BRCA2 tumor suppressor is a DNA double-strand break (DSB) repair factor essential for maintaining genome integrity. BRCA2-deficient cells spontaneously accumulate DNA-RNA hybrids, a known source of genome instability. However, the specific role of...
LA  - en
KW  - BRCA2
KW  - DNA double-strand breaks
KW  - DNA-RNA hybrids
KW  - R-loops
KW  - homologous recombination
KW  - BRCA2 Protein
KW  - Cell Line, Tumor
KW  - DEAD-box RNA Helicases
KW  - DNA Breaks, Double-Stranded
KW  - HEK293 Cells
KW  - Humans
KW  - Nucleic Acid Heteroduplexes
KW  - Protein Binding
KW  - Recombinational DNA Repair
TI  - BRCA2 promotes DNA-RNA hybrid resolution by DDX5 helicase at DNA breaks to facilitate their repair‡.
TY  - research article
VL  - 40
ER  -