RT Journal Article T1 Role of Age and Sex in the Diagnosis of Early-stage Malignant Melanoma: A Cross-Sectional study. A1 Moreno-Ramírez, David A1 Ojeda-Vila, Teresa A1 Ríos-Martín, Juan J A1 Nieto-García, Adoración A1 Ferrándiz, Lara K1 Malignant melanoma K1 Prognostic predictors K1 Thin melanoma K1 Early-stage malignant melanoma K1 Age K1 Sex K1 Estudios transversales K1 Modelos logísticos K1 Melanoma AB Age and sex have been identified as predictors of outcome in malignant melanoma (MM). This aim of this multicentre, cross-sectional study was to analyse the role of age and sex as explanatory variables for the diagnosis of thin MM. A total of 2430 patients with MM were recruited. Cases of in situ-T1 MM were more frequent than T2-T4 MM (56.26% vs. 43.74%). Breslow thickness increased throughout decades of life (analysis of variance (ANOVA) p < 0.001), with a weak correlation between Breslow thickness and patient's age (r   = 0.202, p < 0.001). Breslow thickness was significantly less in women (1.79 vs. 2.38 mm, p = 0.0001). Binary logistic regression showed a significant (p < 0.001) odds ratio for age 0-29 years (1.18), and 30-59 years (1.16), and for women (1.09). Age and sex explained 3.64% of the variation observed in Tis-T1 frequency (R2 = 0.0364). Age and sex appear to explain a low percentage of the variation in the early detection of MM. PB Society for the Publication of Acta Dermato-Venereologica SN 0001-5555 YR 2015 FD 2015-11-04 LK http://hdl.handle.net/10668/2152 UL http://hdl.handle.net/10668/2152 LA en NO Moreno-Ramírez D, Ojeda-Vila T, Ríos-Martín JJ, Nieto-García A, Ferrándiz L. Role of Age and Sex in the Diagnosis of Early-stage Malignant Melanoma: A Cross-Sectional study. Acta Derm. Venereol. 2015; 95(8):940-2 NO Journal Article; DS RISalud RD Apr 19, 2025